Friday, March 29, 2013

York researchers unveil the driving force behind prostate cancer

In a new study, researchers from the University of York have made a major discovery, finding that the presence of specific gene, in cancer stem cells, is the main driving force behind most types of prostate cancer. The researchers, led by Norman Maitland, believe that their study may open the way for developing new drugs that will target and destroy cancer stem cells, thus leading to more effective treatments.

Maitland and his team have been working on prostate cancer stem cells for a long time and were actually the first to isolate such cells in 2005. Since then, they have been researching on how these cells spread, proliferate and why, unlike normal cancer cells, are so resistant to conventional treatments like chemotherapy and radiation.

According to Maitland, their discovery is a "fundamental shift" in how scientists believe "solid cancers start". Professor further explained, that up until today it was thought that cancer cells arise from normal, healthy stem cells that went wrong somewhere.

?In blood cancers such as leukaemia, DNA is rearranged during an event known as chromosomal translocation, which results in a mutant protein that drives cancer progression. Although similar rearrangements have recently been discovered in solid cancers, until now, they have not been considered as stem cell functions. Our work has challenged this idea.??said Maitland

Maitland continues by explaining his team's findings:

?The cells become selfish by surviving outside normal controls that exist in the prostate and thrive at the expense of their neighbours, ensuring that the genetic accident becomes permanent and passed from generation to generation. This process appears to be essential for the initiation of prostate cancer.?

According to the study, these "accidents" are the result of a specific gene, called ERG, which lies within cancer stem cells. When this gene is inappropriately activated, it causes the stem cells to renew more often.

The study was funded by the charity Yorkshire Cancer Research. Kathryn Scott, head of the charity, is very excited with the findings saying that it gives us a deeper understanding of what happens during the first stages of prostate cancer, adding that the study will allow the development of new therapies targeting the aforementioned gene. Ideally, such a therapy would kill all cancer stem cells surviving conventional treatments (e.g. chemotherapy), thus significantly reducing any future risks of prostate cancer relapse & metastasis.

Prostate cancer is a type of cancer that develops in the prostate. In most cases prostate tumours grow slowly, often causing no symptoms until it is in an advanced stage.Some common symptoms associated with prostate cancer are:

  • Pain
  • Difficulty in urinating
  • Problems during sexual intercourse
  • Erectile dysfunction

What is prostate cancer, by?Dr. Larry Bans

Recent, Related Posts

Reference

Polson, E., Lewis, J., Celik, H., Mann, V., Stower, M., Simms, M., Rodrigues, G., Collins, A., & Maitland, N. (2013). Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells Nature Communications, 4 DOI: 10.1038/ncomms2627

Source: http://www.stemcellsfreak.com/2013/03/prostate-cancer-stem-cels.html

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Humongous extinct bird egg up for auction. Where did it come from?

The fine arts auction house Christie's is auctioning off a huge, partly fossilized egg laid by an elephant bird, an extinct creature native to Madagascar. The starting price: $45,000.

By Eoin O'Carroll,?Staff / March 28, 2013

Christie's scientific specialist James Hyslop poses for photographs with a sub-fossilized pre-17th century Elephant Bird egg at the auction house's premises in London. The extinct Elephant Bird species was native to Madagascar and among the heaviest known birds.

Matt Dunham/AP

Enlarge

Larger than a rugby ball and several hundred years old, a giant, partly fossilized egg laid by an extinct bird is set to be auctioned by Christie's. The auction house expects the egg to fetch up to $45,000.

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James Hyslop, the Christie's scientific specialist shown in the Magritte-esque photo above, told the BBC that the type of egg is "the largest egg ever laid by any animal."

The egg is "bigger than dinosaur eggs," said Hyslop.

Of course, phylogenetically speaking, birds?are?dinosaurs, a fact that is easier to believe when you consider the creature that dropped this particular ovum, the elephant bird.

The elephant bird, if you haven't guessed by its name and the size of the egg, was big. Bigger, in fact, than the biggest living bird, the African ostrich. Like the African ostrich, the elephant bird was flightless and from Africa ? Madagascar to be exact. But unlike the African ostrich, it stood over 10 feet tall and weighed up to 800 lbs.?In short, it's not the sort of creature you'd like to meet in a dark alley, unless you happen to be a paleoornithologist?with a tranquilizer rifle.

Elephant birds, a term that comprises up to four species, were common on Madagascar through the 17th century. They are thought to have been driven out of existence by humans, either directly through hunting or indirectly through diseases carried by poultry brought to the island.

How did the elephant bird get so big? It's an example of island gigantism, a phenomenon by which animals on islands tend to evolve to be much larger than their mainland counterparts. Island gigantism often occurs when islands make poor habitats for large predatory mammals, either because they offer limited ranges or because the mammals can't cross the water to get there in the first place. In the absence of such predators, other animals can evolve to fill their niches. Either that, or the lack of predators allow them to grow larger, because there is no need to hide or escape. But?when humans arrive on an island, its giants tend to go extinct. ?

Examples of island gigantism can be found with Komodo dragons, Galapagos tortoises, and the Flores giant rat. ?

In 1894, the science fiction author H.G. Wells published a short story about a man who discovers an ancient elephant bird egg, which subsequently hatches.

Source: http://rss.csmonitor.com/~r/feeds/science/~3/JAQX9rt05_E/Humongous-extinct-bird-egg-up-for-auction.-Where-did-it-come-from

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Thursday, March 28, 2013

Home Skillet - Cooking Blog: Lemony-Pepper Browned Butter ...


You know those people who are so nature-y....the ones who go on hikes instead of walks, who camp instead of staying in facilities with toilets, who bike and have edible gardens and are just so "one with nature."

I'm not one of them.

I wish I was. But I'm not.

I pee a lot. Like a lot. As soon as emailing became a thing my best friend (hi Jess!) was forwarding me links to pharmaceuticals helping overactive bladder.

So I get nervous being away from civilization. Away from toilets. Away from toilet paper.

And correlated with (caused by?) this issue, I drink a lot of water. And water is heavy. So I never have enough. And I get hungry. And food supplies must be hauled around as well.

And I sunburn. Ohhhh I sunburn. This wasn't always the case. In my younger days I was able to procure a respectable tan. But not anymore. Now all I can get is a respectable burn.

So while I totally promote environmentalist values and advocate a response to climate change (seriously, what's going on with that? aren't we going to at least try to do something??), I'm much better at experiencing nature from afar (unless we count the beach, I'm pro-beach). I'd much rather be at home on the couch with some popcorn and water and a toilet just footsteps away, watching Planet Earth. ?And instead of raising my own produce, I will go to a market to obtain them - in this case, asparagus, and mushrooms, and spinach. ?And then head to the kitchen, with its pots and pans and utensils, and turn those into a meal with pasta and browned butter vinaigrette. ?I am forever grateful for civilization.

Adapted from Cooking Light's Roasted Asparagus with Browned Butter and Balsamic Vinegar.

Ingredients
2 bundles of asparagus, ends removed, chopped into 1-inch pieces
drizzle of extra virgin olive oil
kosher salt, to taste
freshly ground black pepper, to taste
8 ounces whole wheat elbow noodles
8 ounces cremini mushrooms, chopped
3 cups spinach leaves

Vinaigrette:
4 tablespoons unsalted butter
4 teaspoons soy sauce
2 teaspoons balsamic vinegar
1/2 teaspoon lemon zest
2 teaspoons lemon juice
lots of freshly ground black pepper

Parmesan cheese, for serving


Instructions
Cook pasta in a large pot of salted water, according to package directions.

To make the asparagus: Heat oven to 400. ?Drizzle oil on asparagus. ?Sprinkle salt and pepper. ?Roast for 10-15 minutes, until they have some of that delicious brown color. ?Once done, remove from oven and set aside.


To make the mushrooms: Heat olive oil in a large saut? pan over high heat. Add the chopped mushrooms. Stir continuously, allowing the mushrooms to absorb the butter and oil mixture. After a few minutes, the mushrooms will brown. Set aside.


To make the vinaigrette: Melt butter in a small skillet over medium heat; let it cook for about three minutes or until it has turned brown and has a nutty fragrance. ?Remove from heat. ?Stir in soy sauce, balsamic vinegar, lemon zest, and lemon juice. ?Add a generous amount of freshly ground black pepper.

In a large pot (I just used the pot that was used for making the pasta), mix asparagus, pasta, and mushrooms all together. ?Toss in the spinach leaves. ?Drizzle dressing over the pasta and vegetables. ?Use tongs to coat. ?Gently heat the pasta over low heat. ?Once the pasta has been warmed and the spinach is slightly wilted, serve. ?Top each pasta bowl with a sprinkle of Parmesan cheese.


Source: http://hskillet.blogspot.com/2013/03/lemony-pepper-browned-butter.html

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Better-educated parents feed children fewer fats and less sugar

Mar. 27, 2013 ? The level of education of parents has an influence on the frequency with which their children eat foods linked to obesity. The children of parents with low and medium levels of education eat fewer vegetables and fruit and more processed products and sweet drinks.

An international group of experts from eight European countries have analysed the relation between parents' levels of education and the frequency with which their children eat food linked to overweight.

The Identification and prevention of dietary- and lifestyle-induced health effects in children and infants (IDEFICS) study includes data from 14,426 children aged between two and nine from eight European countries: Italy, Estonia, Cyprus, Belgium, Sweden, Hungary, Germany and Spain.

The results published in the journal Public Health Nutrition confirm that parents with a lower level of education feed their children food rich in sugars and fats more often than those parents with a higher level of education, who feed their children more products of a higher nutritional quality, including vegetables, fruit, pasta, rice and wholemeal bread.

"The greatest differences among families with different levels of education are observed in the consumption of fruit, vegetables and sweet drinks," explains Juan Miguel Fern?ndez Alvira, the author of the work and researcher from the University of Zaragoza to SINC.

For the authors, this implies a greater risk of developing overweight and obesity in children from less advantaged socio-cultural groups. "The programmes for the prevention of childhood obesity through the promotion of healthy eating habits should specifically tackle less advantaged social and economic groups, in order to minimise inequalities in health," concludes Fern?ndez Alvira.

Childhood nutrition

Childhood, from two to fourteen years old, is a growth period during which the requirements for energy and nutrients increase. Nevertheless, the World Health Organisation warns of the importance of monitoring the diet of the youngest members of society, as almost 40 million children under the age of five suffered from overweight in 2010.

In fact, recommendations for children over two do not differ greatly from those for adults. Their diet should include cereals, fruit, vegetables, dairy products, lean meats, fish, poultry, eggs and nuts.

Dieticians and nutritionists recommend that parents offer children a wide variety of foods and avoid using food as a method to award or punish behaviour. Experts believe that this age group can decide how much to eat, provided the food is always healthy and nutritious.

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Story Source:

The above story is reprinted from materials provided by Plataforma SINC, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Juan Miguel Fern?ndez-Alvira, Theodora Mouratidou, Karin Bammann, Antje Hebestreit, Gianvincenzo Barba, Sabina Sieri, Lucia Reisch, Gabriele Eiben, Charalampos Hadjigeorgiou, Eva Kovacs, Inge Huybrechts, Luis A Moreno. Parental education and frequency of food consumption in European children: the IDEFICS study. Public Health Nutrition, 2012; 16 (03): 487 DOI: 10.1017/S136898001200290X

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/nutrition/~3/iB5hZbA7BQU/130327092742.htm

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Tuesday, March 12, 2013

Researchers find alternative cholesterol-lowering drug for patients who can't tolerate statins

Researchers find alternative cholesterol-lowering drug for patients who can't tolerate statins [ Back to EurekAlert! ] Public release date: 11-Mar-2013
[ | E-mail | Share Share ]

Contact: Jess C. Gomez
jess.gomez@imail.org
801-718-8495
Intermountain Medical Center

SAN FRANCISCO Heart patients who can't tolerate the side effects of cholesterol-lowering drugs may have a new option, according to a new study by researchers from the Intermountain Heart Institute at Intermountain Medical Center in Salt Lake City.

Researchers found that pitavastatin, a newer cholesterol-lowering drug, may reduce the risk of heart attack, stroke and even death in up to 68 percent of patients with high cholesterol who can't tolerate other cholesterol-lowering medications due to side effects.

Researchers are presenting the results of this study today (Monday, March 10) at the American College of Cardiology's Annual Scientific Session in San Francisco.

The findings are important because up to 15 percent of the nation's heart patients can't tolerate other statin medications, currently the most effective cholesterol-lowering agents available.

"Many of the patients who were not able to tolerate other statins developed side effects, such as myalgia or severe muscle aches. However, our study shows that pitavastatin may be a more tolerable statin that patients can take that will be effective in lowering their cholesterol, and may even save their lives," said Brent Muhlestein, MD, cardiologist at the Intermountain Heart Institute at Intermountain Medical Center, and lead researcher for the study.

The Research

The research team identified 40 patients who had tried at least two other statins and tested them to see if they could tolerate pitavastatin, and if it was effective in lowering their LDL or "bad" cholesterol.

All patients received initial baseline testing, including fasting LDL cholesterol levels. They were then given 2 mg of pitavastatin (also known as Livalo), per day. Those who could tolerate it were then tested again to see if their LDL cholesterol had been reduced.

Findings

  • 68 percent of the study participants were able to tolerate the side-effects of pitavastatin.
  • Pitavastatin lowered cholesterol by an average of 34 percent.
  • Patients who could best tolerate the drug were males with no history of heart disease or diabetes.

"We're excited about these findings," said Dr. Muhlestein. "If patients are having a hard time taking older statins, they should try this newer option. We believe the side effects of this drug differ from other statins because pitavastatin is water-soluble and metabolizes differently."

The Intermountain study also confirmed that pitavastatin is far more effective than any other non-statin option.

Ezetimibe (Zetia), for example, is a drug that blocks the absorption of cholesterol and is a non-statin treatment option, but it only lowers bad cholesterol by 18 to 20 percent. Another option is healthy margarine, but that only lowers it by 5 to 10 percent. Pitavastatin, by contrast, lowered cholesterol by an average of 34 percent, according to the study.

###

Other members of the research team include: Bobbi Hollaway; Cheryl Jensen; Haeli Steinmann; Heidi T. May, PhD; Donald Lappe, MD; Jeffrey Anderson, MD; and Joseph Muhlestein, MD.

The Intermountain Medical Center Heart Institute at Intermountain Medical Center in Salt Lake City is one of the premier cardiac centers in the country. Intermountain Medical Center is the flagship medical campus for the Intermountain Healthcare system.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Researchers find alternative cholesterol-lowering drug for patients who can't tolerate statins [ Back to EurekAlert! ] Public release date: 11-Mar-2013
[ | E-mail | Share Share ]

Contact: Jess C. Gomez
jess.gomez@imail.org
801-718-8495
Intermountain Medical Center

SAN FRANCISCO Heart patients who can't tolerate the side effects of cholesterol-lowering drugs may have a new option, according to a new study by researchers from the Intermountain Heart Institute at Intermountain Medical Center in Salt Lake City.

Researchers found that pitavastatin, a newer cholesterol-lowering drug, may reduce the risk of heart attack, stroke and even death in up to 68 percent of patients with high cholesterol who can't tolerate other cholesterol-lowering medications due to side effects.

Researchers are presenting the results of this study today (Monday, March 10) at the American College of Cardiology's Annual Scientific Session in San Francisco.

The findings are important because up to 15 percent of the nation's heart patients can't tolerate other statin medications, currently the most effective cholesterol-lowering agents available.

"Many of the patients who were not able to tolerate other statins developed side effects, such as myalgia or severe muscle aches. However, our study shows that pitavastatin may be a more tolerable statin that patients can take that will be effective in lowering their cholesterol, and may even save their lives," said Brent Muhlestein, MD, cardiologist at the Intermountain Heart Institute at Intermountain Medical Center, and lead researcher for the study.

The Research

The research team identified 40 patients who had tried at least two other statins and tested them to see if they could tolerate pitavastatin, and if it was effective in lowering their LDL or "bad" cholesterol.

All patients received initial baseline testing, including fasting LDL cholesterol levels. They were then given 2 mg of pitavastatin (also known as Livalo), per day. Those who could tolerate it were then tested again to see if their LDL cholesterol had been reduced.

Findings

  • 68 percent of the study participants were able to tolerate the side-effects of pitavastatin.
  • Pitavastatin lowered cholesterol by an average of 34 percent.
  • Patients who could best tolerate the drug were males with no history of heart disease or diabetes.

"We're excited about these findings," said Dr. Muhlestein. "If patients are having a hard time taking older statins, they should try this newer option. We believe the side effects of this drug differ from other statins because pitavastatin is water-soluble and metabolizes differently."

The Intermountain study also confirmed that pitavastatin is far more effective than any other non-statin option.

Ezetimibe (Zetia), for example, is a drug that blocks the absorption of cholesterol and is a non-statin treatment option, but it only lowers bad cholesterol by 18 to 20 percent. Another option is healthy margarine, but that only lowers it by 5 to 10 percent. Pitavastatin, by contrast, lowered cholesterol by an average of 34 percent, according to the study.

###

Other members of the research team include: Bobbi Hollaway; Cheryl Jensen; Haeli Steinmann; Heidi T. May, PhD; Donald Lappe, MD; Jeffrey Anderson, MD; and Joseph Muhlestein, MD.

The Intermountain Medical Center Heart Institute at Intermountain Medical Center in Salt Lake City is one of the premier cardiac centers in the country. Intermountain Medical Center is the flagship medical campus for the Intermountain Healthcare system.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-03/imc-rfa031113.php

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Which Encryption Apps Are Strong Enough to Help You Take Down a Government?

It seems like these days I can't eat breakfast without reading about some new encryption app that will (supposedly) revolutionize our communications — while making tyrannical?regimes fall like cheap confetti. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/SZOdCEUYcsY/which-encryption-apps-are-strong-enough-to-help-you-take-down-a-government

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Monday, March 11, 2013

New checklist brings information about Cucurbitaceae up to date

New checklist brings information about Cucurbitaceae up to date [ Back to EurekAlert! ] Public release date: 11-Mar-2013
[ | E-mail | Share Share ]

Contact: Susanne Renner
renner@lrz.uni-muenchen.de
Pensoft Publishers

In 2010, it was shown that melons and cucumbers can be traced back to India. Because of the importance of the region for an understanding of Cucurbitaceae evolution and diversity, a new checklist of the Cucurbitaceae of India was produced to update the information on that family. The study was published in the open access journal PhytoKeys.

Vegetables are essential components of a healthy daily diet, not just in India but around the globe. Compared to grains and pulses, however, vegetables are under-investigated taxonomically, and information on their genome is scarce. The cucumber family, Cucurbitaceae, includes many of our favorite foods: pumpkins, melon, cucumber, watermelon, bottle gourds, and bitter gourd. Molecular data have recently revealed that both cucumber (Cucumis sativus L.) and melon (Cucumis melo L.) are indigenous to India and likely to have originated from the foothills of the Himalayas.

Arun Pandey from the Department of Botany, University of Delhi, India and Susanne Renner from the Departments of Systematic Botany and Mycology, University of Munich, Germany decided to produce a checklist of the Cucurbitaceae of India that would bring up-to-date the information available for that family. The list treats 400 relevant names and provides information on the collecting locations for all type specimens. The list includes 94 species (10 of them endemic to India) from 31 genera.

For each species, the checklist provides distributional information, electronic links to images of living or dried plants, and information on publicly available DNA sequences. Of the 94 species, 79% have DNA sequences in GenBank, albeit rarely stemming from Indian material. The most species-rich genera are Trichosanthes with 22 species, Cucumis with 11 (all but two wild), and the bitter gourd genus, Momordica, with eight. The checklist also includes a phylogenetic reconstruction of the family that shows the DNA-based placement of the 31 Indian genera relative to the World's remaining Cucurbitaceae.

Dr. Susanne Renner, one of the authors of the article, comments: "Updating and summarising the available information on Indian Cucurbitaceae and linking it to molecular data and images may help to focus phylogenetic and floristic research on poorly known species, and potentially strengthen conservation efforts. It may also provide vital genetic information to improve the current varieties of pumpkins, cucumbers, and their relatives."

###

Original Source:

Renner SS, Pandey AK (2012) The Cucurbitaceae of India: Accepted names, synonyms, geographic distribution, and information on images and DNA sequences. PhytoKeys 20: 53, doi: 10.3897/phytokeys.20.3948

Licensing

This press release is available under the Creative Commons Attribution 3.0 License. It is expected to link back to the original article.

Posted by Pensoft Publishers.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


New checklist brings information about Cucurbitaceae up to date [ Back to EurekAlert! ] Public release date: 11-Mar-2013
[ | E-mail | Share Share ]

Contact: Susanne Renner
renner@lrz.uni-muenchen.de
Pensoft Publishers

In 2010, it was shown that melons and cucumbers can be traced back to India. Because of the importance of the region for an understanding of Cucurbitaceae evolution and diversity, a new checklist of the Cucurbitaceae of India was produced to update the information on that family. The study was published in the open access journal PhytoKeys.

Vegetables are essential components of a healthy daily diet, not just in India but around the globe. Compared to grains and pulses, however, vegetables are under-investigated taxonomically, and information on their genome is scarce. The cucumber family, Cucurbitaceae, includes many of our favorite foods: pumpkins, melon, cucumber, watermelon, bottle gourds, and bitter gourd. Molecular data have recently revealed that both cucumber (Cucumis sativus L.) and melon (Cucumis melo L.) are indigenous to India and likely to have originated from the foothills of the Himalayas.

Arun Pandey from the Department of Botany, University of Delhi, India and Susanne Renner from the Departments of Systematic Botany and Mycology, University of Munich, Germany decided to produce a checklist of the Cucurbitaceae of India that would bring up-to-date the information available for that family. The list treats 400 relevant names and provides information on the collecting locations for all type specimens. The list includes 94 species (10 of them endemic to India) from 31 genera.

For each species, the checklist provides distributional information, electronic links to images of living or dried plants, and information on publicly available DNA sequences. Of the 94 species, 79% have DNA sequences in GenBank, albeit rarely stemming from Indian material. The most species-rich genera are Trichosanthes with 22 species, Cucumis with 11 (all but two wild), and the bitter gourd genus, Momordica, with eight. The checklist also includes a phylogenetic reconstruction of the family that shows the DNA-based placement of the 31 Indian genera relative to the World's remaining Cucurbitaceae.

Dr. Susanne Renner, one of the authors of the article, comments: "Updating and summarising the available information on Indian Cucurbitaceae and linking it to molecular data and images may help to focus phylogenetic and floristic research on poorly known species, and potentially strengthen conservation efforts. It may also provide vital genetic information to improve the current varieties of pumpkins, cucumbers, and their relatives."

###

Original Source:

Renner SS, Pandey AK (2012) The Cucurbitaceae of India: Accepted names, synonyms, geographic distribution, and information on images and DNA sequences. PhytoKeys 20: 53, doi: 10.3897/phytokeys.20.3948

Licensing

This press release is available under the Creative Commons Attribution 3.0 License. It is expected to link back to the original article.

Posted by Pensoft Publishers.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-03/pp-ngs031113.php

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Sunday, March 10, 2013

Vt. paper defends 'fry Rice' sign supporting team

A copy of the Caledonian Record lies on display, Friday, March 8, 2013 in Montpelier, Vt. The Vermont newspaper is being criticized for a poster designed to boost the local high school basketball team before it played in the state championship. On Thursday, the Caledonian Record of St. Johnsbury ran a full-page poster on the back of its main section that included the term ?Fry Rice? using a typeface that mimicked Chinese calligraphy. In a letter to the Caledonian Record publisher, the Asian American Journalists Association said it was appalled by the page?s racist undertones. The letter asked the paper to acknowledge its lapse in judgment. (AP Photo/Toby Talbot)

A copy of the Caledonian Record lies on display, Friday, March 8, 2013 in Montpelier, Vt. The Vermont newspaper is being criticized for a poster designed to boost the local high school basketball team before it played in the state championship. On Thursday, the Caledonian Record of St. Johnsbury ran a full-page poster on the back of its main section that included the term ?Fry Rice? using a typeface that mimicked Chinese calligraphy. In a letter to the Caledonian Record publisher, the Asian American Journalists Association said it was appalled by the page?s racist undertones. The letter asked the paper to acknowledge its lapse in judgment. (AP Photo/Toby Talbot)

(AP) ? A Vermont newspaper defended itself Saturday against accusations of racism over a poster it published in support of a local sports team that read "fry Rice" in type associated with Chinese calligraphy, saying it meant no offense and simply wanted to play on words.

The back-page poster, printed in Thursday's editions, was intended to support St. Johnsbury Academy's basketball team in its game against Rice Memorial High School in South Burlington, the Caledonian Record wrote in an unsigned editorial (http://bit.ly/Yj75aB ).

"We sought a simple play on words in support of an extraordinary group of local student athletes. Indulging our critics for a moment, the outcry reminds us that racial and ethnic stereotypes can offend ? regardless of intent," the editorial said.

The editorial acknowledged that the poster's wordplay, punctuated by the chosen font, "evoked a particular ethnic cuisine" but did not constitute racism.

"We don't concede, however, that the use of imagery with any racial, ethnic or religious inference is to inherently debase that race/ethnicity/religion," the paper said.

"A fair accusation of racism would at least pre-require the reference to actually be demeaning or degrading," the editorial said. "Simply invoking ethnic customs (food, dress, design) doesn't do that, nor does it suggest any kind of characteristic about the culture, its people or a history of oppression by the majority.

But the editorial missed the point, said the president of the Asian American Journalists Association, who had criticized the poster after it was published.

"I'm not criticizing the Caledonian Record for rooting for their home team," said Paul Cheung, the association's president. While Cheung does not believe the newspaper's intention was to be racist, it showed "a lapse of judgment and poor taste."

"It evoked a racial undertone and a negative stereotype," said Cheung, who is also interactive and graphics editor for The Associated Press.

St. Johnsbury Academy ended up losing the game to Rice Memorial.

A private school, St. Johnsbury Academy serves local students and also has boarding students from across the world, including Asia. Academy Headmaster Tom Lovett said Friday that none of the school's Asian students were offended by the poster.

"Overall, our students often see such things as a way to celebrate their culture, not demean it. And in this case, we chose to follow our students' lead and look at the Caledonian's intent, not taking offense where none was intended," Lovett said.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-03-09-US-Poster-Complaint/id-5c0e3d61ad374c5589c46d1677cf544b

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Friday, March 8, 2013

Small businesses marketing SMS opportunities | Widgeon Hill Winery

Since the entire purpose of starting up a business is to make profit and expand the business, many business owners are looking for ways and new avenues to achieve these outcomes. A quick search over the internet or the best marketing campaign tools will provide one with numerous search results that it may leave you confused as to the best choice that may suit your business. One thing you should take into account when choosing the marketing tool to adopt should be the nature of the business and the number and type of customers or client you intend to attract. If you really work along these guidelines, there is a high tendency that you can never go wrong in your choice of tool.

As a business owner who has small businesses, you should consider capitalizing more on marketing SMS. These marketing sms are a good and affordable way to put your business in the limelight and still be able to always smile to the bank. They are so cheap when in comparison with other marketing tools and are a sure way of keeping in touch with your customers. Why should I keep in touch with my customers? Customers are the life of the business, their presence in your business guarantees your profit and corresponding growth. A good customer care reception is powerful to keep your customers captivated but with sms marketing tool, you get to inform them about new and special offers without them walking through your business door.

Customers always like to be treated specially and lovingly. When they can guarantee that they are getting their moneys worth, there is a large chance they will always come back for more. By gaining their trust, you can communicate important information concerning the business through sms to their phones. Although not frequently, the sms tool can keep them abreast with you product and service offers.

Source: http://www.widgeonhill.com/small-businesses-marketing-sms-opportunities.html

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So Sweet! Diddy Takes His Twins to Their First Dance

"On [the] way to my 1st father daughter dance!!! I'm so EXCITED!!!" the proud papa wrote, sharing the photo with his fans Friday on Instagram.

Source: http://feeds.celebritybabies.com/~r/celebrity-babies/~3/PWgELKc5BtM/

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Thursday, March 7, 2013

Personal Bankruptcy And Why It Might Be The Right Choice For You ...

Is your financial situation bad and you think the only solution is bankruptcy? Do not despair, because there are other people in the same boat. Many people are filing bankruptcy to relieve financial hardship. The following article offers many great tips on bankruptcy that can be very helpful when faced with this situation.

Know that bankruptcy can be much better for your finances than missing payments or making late payments on debts. While bankruptcy will haunt your credit history for up to ten years, your damaged credit will start healing right away. The whole point of bankruptcy is to give you a second chance.

If you are facing financial difficulty, it may not be wise to go through with a divorce. A lot of individuals get a divorce and file for bankruptcy immediately because they did not plan for the troubles that they will be experiencing financially. It is always wise to think twice about divorcing.

Bankruptcy is a difficult and stressful process, and you will need all the help you can get. Engage a competent lawyer in order to avoid excess stress and keep everything on track. Don?t think that the highest priced attorney is the best. Think about quality rather than cost when hiring an attorney. Speak with trusted people, check the BBB and take advantage of the free bankruptcy attorney consultations. When looking at bankruptcy attorneys, consider sitting in on one of their court hearings to find out how they handle the case.

If you are unable to get a homestead exemption when filing for Chapter 7, you might consider filing for Chapter 13 bankruptcy to cover your mortgage. It might even be better to convert from a Chapter 7 to a Chapter 13; talk to your lawyer about this.

Know the bankruptcy code backwards and forwards before filing. For instance, for 365 days before filing, no one is able to receive assets from the filer. Moreover, a filer is prohibited from spending or incurring extra debt prior to their bankruptcy filing.

Look at all the alternatives to bankruptcy before filing. Before filing, talk with an attorney who can help you weigh all of your options. Loan modification plans on home loans are a great example of this. The lender can help your financial situation by getting interest rates lowered, dropping late charges, and in some cases will allow you to pay the loan over a longer period of time. Making arrangements with the creditors to make reasonable payments towards you debt is a much better plan than bankruptcy because the lender simply wants the loan repaid.

Filing for personal bankruptcy is nothing to be ashamed of. Many people will get depressed and think they?ve failed when they need to file. If you?ve done adequate research and rationalized about whether it?s the best option, do your best to look at it as a step towards success with your finances.

If you think you may file for bankruptcy, be aware that you cannot transfer assets to anyone else in the 12 months prior to filing. Courts see this as an attempt to hide your assets, and this practice can cause your petition to be dismissed. Certain assets are automatically safe from creditors, no matter how much you owe. Regardless, hiding assets in this manner is never acceptable, so make sure to wait to file if you have recently transferred any assets.

Realize that there is a chance your declaration of bankruptcy may be denied and be prepared for this possibility. Read all the laws pertaining to bankruptcy in your state or consult a qualified attorney to ensure that you are aware of all possible outcomes.

Always protect your house. Filing for bankruptcy does not mean you have to lose your home. It is entirely possible that you will be able to keep your home. This is dependent upon the your home?s value and whether or not you have taken a second mortgage. It can be worthwhile to understand the homestead exemption law to see if you qualify to keep living in your home under the financial threshold requirements.

Many bankruptcy lawyers offer free consultations, so go to several before choosing one. Be certain that the person you meet with is really a lawyer. Avoid meeting with paralegals or legal assistants because they cannot give you legal advice. Take some time to talk to different lawyers to find one that fits your needs, and meshes well with you.

Is a second employment position for you possible? Rather than going the bankruptcy route, discuss the situation with your debtors and explain to them everything you are doing to increase your income. Your creditors will likely be willing to accommodate you, freeing you from the need to declare bankruptcy.

If you really want to keep your vehicle, speak with your lawyer about possible choices. Most of the time Chapter 7 bankruptcy will allow your payments to be lowered. There are a few requirements that you have to meet to be eligible, though. You have to have bought the car more than 2.5 years ago, your loan?s interest rate needs to be over a certain amount, and your employment history has to be good.

Like you have heard, you are not alone in your financial problems. Others just like you are filing for bankruptcy as well. However, others who are filing for bankruptcy do not have the advice that you have just been given. Use the helpful tips in this article to assure your bankruptcy goes off without a hitch.

Think again if you had the impression you knew everything about stock market newsletter before reading this article. There is a lot more information for you out there. As long as you can make it a priority to continue learning, you will do well. This is simply the start.

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Source: http://www.financemarkettoday.com/2013/03/07/personal-bankruptcy-and-why-it-might-be-the-right-choice-for-you/

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Filipino cardinal stirs papal talk with rapid rise

(AP) ? Asia's most prominent Roman Catholic leader knows how to reach the masses: He sings on stage, preaches on TV, brings churchgoers to laughter and tears with his homilies. And he's on Facebook.

But Philippine Cardinal Luis Antonio Tagle's best response against the tide of secularism, clergy sex abuse scandals and rival-faith competition could be his reputation for humility. His compassion for the poor and unassuming ways have impressed followers in his homeland, Asia's largest Catholic nation, and church leaders in the Vatican.

Tagle's rising star has opened a previously unimaginable possibility: An Asian pope.

The Filipino prelate's chances are considered remote, as many believe that Latin America or Africa ? with their faster growing Catholic flocks ? would be more logical choices if the papal electors look beyond Europe. But even the hint of papal consideration has electrified many in the heavily Catholic Philippines, where past pontiffs had been welcomed by millions with rock-star intensity.

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EDITOR'S NOTE: As the Roman Catholic Church prepares to elect a successor to Pope Benedict XVI, The Associated Press is profiling key cardinals seen as "papabili" ? contenders to the throne. In the secretive world of the Vatican, there is no way to know who is in the running, and history has yielded plenty of surprises. But these are the names that have come up time and again in speculation. Today: Luis Antonio Tagle.

___

"It'll bring such immense glory to us and our country," said Leo Matias, one of several waiters at a Chinese restaurant in Manila's suburban Quezon city who served dinner to Pope John Paul II when he visited in 1995.

The restaurant has displayed the set of spoon, fork, table napkin, water goblet and knives ? still unwashed after the pope's meal of grilled fish and fried shrimp.

The talks surrounding Tagle have been fueled by prominent Vatican experts, who see in the boyish-looking cardinal the religious zest, stamina, charisma and communications skills that could energize the church facing crises on many fronts.

John Thavis, a Vatican analyst and author of "The Vatican Diaries," said the 1979 selection of Polish-born John Paul II in 1979 shows the "unthinkable" can occur once the cardinals are closed off in the conclave.

"There are people, even Vatican officials here, who have whispered to me, 'Tagle, he's the man,'" Thavis told The Associated Press.

When asked about the papal buzz, Tagle demurred: "Only a speculation."

"He's an effective communicator and missionary at a time when Catholicism's highest internal priority is a new evangelization," John Allen, a Rome-based analyst, wrote for the National Catholic Reporter.

"Tagle incarnates the dramatic growth of Catholicism outside the West, putting a face on the dynamic and relatively angst-free form of Catholicism percolating in the Southern Hemisphere," he said. "He would certainly be a symbol of the church in the emerging world, but given his intellectual and personal qualities, hardly a hollow one."

Still, Tagle's relative youth ? at 55, he's the second youngest among the cardinals ? could be a liability. Cardinals could be reluctant to risk giving the reins of the Vatican to someone who could reign for decades.

The churchman who last caught the deep adoration of many Filipino Catholics was Cardinal Jaime Sin, who died in 2005. A beloved spiritual leader and moral compass, Sin helped rally multitudes in the massive "people power" revolts that ousted two presidents, including dictator Ferdinand Marcos in 1986.

Sin's death left a vacuum in the church saddled with the task of shepherding Catholics in a country plagued by poverty, divisions, crimes and long-raging Muslim and Marxist insurgencies. Unlike Sin, Tagle was not propelled by any extraordinary events. But people who know him say that Tagle slowly carved a reputation for simple, day-to-day acts that defined him as a man of deep faith and intellect.

The younger of two children of a pious Catholic couple who worked in a bank, Tagle dreamed of becoming a doctor. But he was redirected by a Jesuit friend to the priesthood at a seminary in the upscale Ateneo de Manila University, where he graduated summa cum laude, according to his theology professor, the Rev. Catalino Arevalo.

He's gifted with great communications skills: A wonderful storyteller with a bent for music, Tagle speaks Italian, French, English, Tagalog and Latin. But he prefers to stay in the background.

"He's not somebody who sort of wants to, by personality, put himself at the center of the stage," Arevalo said. "Now, if he's called to be in front, he has all the capability of doing it."

Tagle took clear positions on church and social issues but was never confrontational or "super militant," Arevalo said. For instance, he encouraged dialogue when he helped lead an unsuccessful church campaign against the government-endorsed health plan that promotes contraceptives.

Tagle was ordained in 1982 and became bishop in 2001 at an old cathedral, about a block from his family's home in Imus just south of Manila.

Aside from his church work, he taught theology in a hilltop seminary, where he lived for about two decades, staying in a room that had no television or air-conditioning, according to seminary staffers.

Even as a bishop, Tagle did not own a car. He took the bus or "jeepney," the popular working-class minibus, to church and elsewhere. He ate with workers and sang for a church charity, impressing many with his baritone voice.

Tagle stood out for his powerful homilies. A few years ago, he started hosting a Sunday gospel show on TV, where he preached and answered questions. Staffers then opened a Facebook page for him, which has jumped to more than 120,000 followers.

Tagle's path at some point crossed with the future pope, then-Cardinal Joseph Ratzinger, who introduced him to John Paul II and reportedly assured the pontiff in jest that the Filipino with a youthful face has received his first communion.

Ratzinger appointed Tagle as a member of the Vatican's International Theological Commission, or ITC, and was impressed with his research work and papers. "I am sure that it was because of what he saw in him at the ITC that Pope Benedict chose him for Manila and then for the red hat" of a cardinal, said the Rev. Joseph Komonchak, one of Tagle's instructors at Catholic University of America.

In October 2011, Benedict declared Tagle the new archbishop of Manila, then just a year later, elevated him to cardinal. Tagle tearfully acknowledged in a recent homily in Imus that he was overwhelmed by his rapid rise. "It's unnerving," he said.

Larger audiences have turned up to listen to his talks and homilies, where he often raised the need for the Catholic Church to reconnect with people. Almost always, Tagle is mobbed like a movie star by fans jostling to get his picture.

"I think many of the cardinals will say, 'It's too much, too soon,'" the professor Arevalo said of Tagle's chances in the conclave. But he added: "We don't know what God wants. If God wants it, God will make up for it."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-03-07-Vatican-Cardinals-Tagle/id-2604157d12194128b6a5fbe6150679af

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Google Focuses on Innovation, Not Stock Price: Exec

Google Officer on Mobile, Partnerships

Nikesh Arora, Google chief business officer, offers insight on the company's soaring stock price in addition to mobile ads and partnerships with other tech giants.

Whether it's new hardware products like Google Glasses or Chromebooks, or the company's other business such as advertising, YouTube, and or mobile, the company has built an empire of products and services that bode well for the company, as well as investors.

(Read More: Google Launching Delivery Service to Take on Amazon)

Google's stock soared to an all-time high on Wednesday at $831.38.

Arora said he doesn't really think about what the company's stock is doing.

"I don't pay attention to our stock price. I used to do that for a living and I decided to stop paying attention," he said.

Instead, he is focused on staying ahead of the latest technologies and on improving Google's current products and services.

"We want to stay relevant in our existing products, that means we have to innovate twice as fast in areas like search, areas like YouTube and areas where people use our services," Arora said.

"You have to make sure we don't miss the next trick. We have to make sure that as consumers keep adapting new technology, new ideas, we have to be there in the forefront. ... And I think we have to keep doing interesting things to change the world," he added.

Even though the company continues to evolve, the core of its revenue still comes from advertising.

Arora said that most advertising revenue still comes from the mature markets, but growth in developing countries is picking up as web access continues to grow.

(Read More: Google Controls Too Much of China's Smartphone Sector: Ministry)

"We should not take away from the fact that there are lots of parts of the world where the Internet is still a huge growth phenomenon, a lot more people are coming on to the Internet, there are lots of business coming on to the Internet," he said. "It's a balance between strong revenue and mature markets and growth of more users on the web, more business on the web, causing more and more advertising to come on."

Source: http://www.cnbc.com/id/100529491

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Wednesday, March 6, 2013

Google's Picasa URL now redirecting to Google+ photo albums

Google's Picasa photo service redirecting to Google photo albums

In yet another bid to seemingly sunset its Picasa branding, Google's redirecting Picasa users who head to its direct URL. Hilariously, that redirection is to Google+ web albums, which ... well, let's just say we haven't been using our G+ photo albums all that much. But perhaps you have, and that's just capital, given that Google is keen on you using that over its flickering, dimmed former star. Of course, should you really, really wish to access the old Picasa directly, you can head to this URL to bypass the redirect. At least until Google forces the end of Picasa through a Google+ Photos push, that is.

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Via: CNET, Google Operating System Blog

Source: Google

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/Qq2lRbmPTtE/

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